Synthesis and Characterization of Coordinatively Unsaturated Copper (II) Complexes of 1,3-Bis(2'-Pyridyl)-1,2-Diaza-2-Butene and Their Antityrosinase Activity

نویسندگان

  • Ratnamala Bendre
  • Anupa Murugkar
  • Subhash Padhye
  • Pallavi Kulkarni
  • Meena Karve
چکیده

The coordinatively unsaturated copper (II) complexes of 1,3-bis(2'-pyridyl)-1,2-diaza-2- butene with different ancillary anions were synthesized which can bind to copper centers of tyrosinase enzyme. The compounds were found to exhibit inhibitory activities against mushroom tyrosinase and the nature and extent of inhibition is modulated according to the type of ancillary anions.

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عنوان ژورنال:
  • Metal-Based Drugs

دوره 5  شماره 

صفحات  -

تاریخ انتشار 1998